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Home > Products >  Pteroic acid

Pteroic acid CAS NO.119-24-4

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Quick Details

  • ProName: Pteroic acid
  • CasNo: 119-24-4
  • Molecular Formula: C14H12N6O3
  • Appearance: Detailed see specifications
  • Application: Pteroic Acid is a constituent as well ...
  • DeliveryTime: Within one week after payment done
  • PackAge: According to customer requirements
  • Port: Any port of China
  • ProductionCapacity: 1 Kilogram/Day
  • Purity: 99%
  • Storage: Store under shade and cool environment...
  • Transportation: During the transportation process, all...
  • LimitNum: 1 Gram
  • Moisture Content: <0.5%
  • Impurity: <0.5%
  • Assay: >98%

Superiority

Hangzhou Benoy Chemical Co., Ltd is a scientific and technological enterprise dedicated to the R & D, production and operation of chemical raw materials, pharmaceutical intermediates and APIs. At present, the company has one R & D center and two production bases. The company has more than 10 full-time personnel engaged in the research and development of APIs and pharmaceutical intermediates, including 2 with doctor's degree, 5 with master's degree, 2 with Professor of Zhejiang University of technology as the chief consultant of the company, with strong scientific research force and rich practical experience. The laboratory is equipped with advanced ultra-high performance liquid chromatography, gas chromatography and relatively complete conventional experimental equipment. Many products have been successfully developed and put into industrial production. The company adheres to the quality and environment policy of "customer first, continuous innovation", and excellent products win good market reputation for the company. At present, the products are exported to Europe, the United States, Southeast Asia and other countries and regions. It is the company's business philosophy to guide technology with information, guarantee quality with technology and win market with quality. The company will give full play to its own advantages and devote itself to the specialization and serialization of pharmaceutical intermediates, so as to provide customers with high-quality, environmental protection and safety products. The company will also be honest, trustworthy, mutually beneficial and co-existence purposes, is willing to sincerely cooperate with customers at home and abroad, hand in hand.
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Details

PTEROIC ACID Basic information
Product Name: PTEROIC ACID
Synonyms: 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid;4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid;4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid;4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid;4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid;NSC 14972;p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid;Pyrofolic acid
CAS: 119-24-4
MF: C14H12N6O3
MW: 312.28
PTEROIC ACID Chemical Properties
Melting point  >400℃
Boiling point  610.0±65.0 °C(Predicted)
density  1.69
storage temp.  2-8°C
PTEROIC ACID Usage And Synthesis
Uses Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.
Enzyme inhibitor This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.
Purification Methods Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]

 

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